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Curious About Prenatal Screening?

Curious about prenatal screening? Dive into the advantages of the IONA Test at Women's Healthcare, guided by experienced gynaecologist Mr. N. Agarwal in London. Discover the personalized care and accurate insights it offers. Ready to ensure a worry-free pregnancy? Explore the IONA Test today!

NIPT Test in London

For some women, pregnancy can be emotionally overwhelming & a difficult period and without the availability of proper prenatal care chances of complications down the line are greater. This is especially true for those conceiving after undergoing a miscarriage treatment or IVF treatment. As such, to have a safe birthing experience, one needs to go for routine pregnancy tests and scans, which is known as IONA Test or IONA Screen Test.

As one of the most advanced non-invasive prenatal screening tests, IONA Test helps detect Trisomy 21, 18 and 13 along with other genetic conditions. From these, many might be familiar with the Down syndrome (Trisomy 21), which is a lifelong genetic condition that causes physical growth delays, characteristic facial features, mild intellectual disability and sometimes heart defects.

The other two genetic condition - Edwards syndrome (Trisomy 18) and Patau syndrome (Trisomy 13) are more severe and often more fatal.

IONA Test is recommended during the early pregnancy check as it helps detect Trisomy condition with 99% accuracy, thus preventing pregnant women from undergoing other invasive follow-up procedure such as amniocentesis or CVS which are not only agonising but also carry a minor risk of miscarriage.

Advantages Of IONA Test

As a private gynaecologist in London, Mr N. Agarwal offers comprehensive pregnancy care and treatments for all women to ensure that the baby and the mother both enjoy good health. The IONA Test is done by using a small sample of blood from the pregnant women, the advantages of IONA Test are as follows;

  • Faster Results – The test sample is sent to a laboratory for analysis and the results are usually available within 3 working days.
  • CE Compliant – IONA Test is a CE quality marked product and as such, provides quality assurance and is reliable.
  • Safe and Secure – There is no risk of miscarriage while doing this test and it is suitable for twin, IVF and surrogate pregnancies.
  • Higher % of AccuracyIONA Test is not only non-invasive but it also has a high rate of up to 99% accuracy in identifying trisomy during pregnancy.

Results Of IONA Test

One of the services that all well woman clinic in London provides is the IONA Test. Expecting parents can largely benefit from this non invasive prenatal testing as it not only gives them peace of mind but also prepares them in case of an untoward result. Interpreting the result of the IONA Test is quite easy as it is simply divided into low risk and high risk.

  • Low Risk – The pregnancy is unlikely to be affected by trisomy 21, 18 or 13.
  • High Risk – The pregnancy has an increased risk for trisomy 21, 18 or 13. In this case, the gynaecologist may advise you to undergo further follow-up tests, prior to confirmation. For high-risk pregnancy, the most common forms of testing are ‘Amniocentesis’ and ‘Chorionic Villus Sampling’ (CVS).

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Who can have the IONA® test?
The IONA® test is a non-invasive prenatal test (NIPT) that screens for chromosomal disorders in the fetus, such as Down syndrome and Edward syndrome. It is suitable for women who are in incubation for 10 weeks and have a singleton pregnancy. Contrastingly, it is not suitable for pregnant women who have undergone organ transplants or have received a blood transfusion potentially in the last 12 weeks.
How accurate is the iona® test?

The IONA® test accuracy rate is 99.8%, and the failure rate is 0.5% for Down syndrome, Edward syndrome, and Patau syndrome.

What is the false positive rate?

The false positive rate of the IONA® test is reported to be less than 1%.

How is the sample taken?

To take a sample of the IONA® test, a simple process of venipuncture is performed on the mother. This blood sample contains a mixture of maternal and fetal DNA. Further, the sample is sent to a laboratory where the cfDNA is extracted and analyzed using revolutionary sequencing methods.

Can I have the IONA® test if I have twins?

Yes, the IONA® test is suitable for having twin pregnancies, but it may not be as accurate as a singleton pregnancy. However, the accuracy of the test may vary depending on the zygosity (including identical and fraternal) of the twins.

Is the IONA® test 100% conclusive?

Despite its high level of accuracy, the IONA® test is not considered 100% definitive. Due to the naturally occurring biological situations in which the DNA of the fetus and the DNA of the placenta differ.

What does IONA® test screen for?

IONA test screens for various chromosomal disorders, such as Down syndrome (Trisomy 21), Edward syndrome (Trisomy 18), and Patau syndrome (Trisomy 13), in developing fetuses during pregnancy.

Why is IONA® better than the current NHS combined test?

The IONA® test determines higher accuracy rates as compared to the NHS combined test. It can also be performed as early as 10 weeks into pregnancy, whereas the NHS combined test can only be held between 11-14 weeks of pregnancy. Lastly, it can detect a wider range of chromosomal disorders compared to the NHS combined tests.

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